Seth Green as Jeff ‘Joker’ Moreau in Mass Effect

'Robot Chicken' creator and actor Seth Green voices the fictional character Jeff "Joker" Moreau in Mass Effect 1 and 2.

Green is the perfect choice to play the caustic, sickly Moreau, who's known for cracking jokes throughout the video game series.

For example, if your character stands around idly he will begin to throw random humorous comments at you. He also has sarcastic remarks at the end of every mission.

Sadly, he never turns into a werewolf. Damn.